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Evaluation of somatostatin and nucleolin receptors for therapeutic delivery in non-small cell lung cancer stem cells applying the somatostatin-analog DOTATATE and the nucleolin-targeting aptamer AS1411.

Cancer stem cells represent the putative tumor-driving subpopulation thought to account for drug resistance, relapse, and metastatic spread of epithelial and other cancer types. Accordingly, cell surface markers for therapeutic delivery to cancer stem cells are subject of intense research. Somatosta...

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Bibliografski detalji
Glavni autori: Sif Holmboe, Pernille Lund Hansen, Helge Thisgaard, Ines Block, Carolin Müller, Niels Langkjær, Poul Flemming Høilund-Carlsen, Birgitte Brinkmann Olsen, Jan Mollenhauer
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science (PLoS) 2017-01-01
Serija:PLoS ONE
Online pristup:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0178286&type=printable
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