Automated reporting of primaquine dose efficacy, tolerability and safety for Plasmodium vivax malaria using a systematic review and individual patient data meta-analysis

Abstract Background The antirelapse efficacy of primaquine is related to the total dose administered, whereas the risks of haemolysis and gastrointestinal intolerance are associated with the daily dose administered. National Malaria Control Programmes require local information on efficacy, tolerabil...

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Hauptverfasser:	Peta Edler, Megha Rajasekhar, David J. Price, Ishag Adam, Ghulam Rahim Awab, Bridget E. Barber, Larissa W. Brasil, Nathália N. Chamma-Siqueira, Cindy S. Chu, Liwang Cui, André Daher, Margarete do Socorro M. Gomes, Lilia Gonzalez-Ceron, Matthew J. Grigg, Harin Karunajeewa, Marcus V. G. Lacerda, Simone Ladeia-Andrade, Toby Leslie, Benedikt Ley, Kartini Lidia, Alejandro Llanos-Cuentas, Rhea J. Longley, Laurens Manning, Daniel Abebe Mekonnen, Wuelton Marcelo Monteiro, Brioni R. Moore, Francois Nosten, Ayodhia Pitaloka Pasaribu, Dhelio B. Pereira, Jeanne Rini Poespoprodjo, Sasithon Pukrittayakamee, Komal Raj Rijal, Kavitha Saravu, André M. Siqueira, Inge Sutanto, Walter R. J. Taylor, Pham Vinh Thanh, Kamala Thriemer, José Luiz F. Vieira, Nicholas J. White, Asnakew K. Yeshiwondim, Lina M. Zuluaga-Idarraga, Philippe J. Guerin, Julie A. Simpson, Ric N. Price, Robert J. Commons, WorldWide Antimalarial Resistance Network (WWARN) Vivax Primaquine Dosing Efficacy, Tolerability and Safety Study Group
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2025-11-01
Schriftenreihe:	Malaria Journal
Schlagworte:	Plasmodium vivax Malaria Primaquine Recurrence Relapse Dose
Online-Zugang:	https://doi.org/10.1186/s12936-025-05642-w
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