Nacre-mimetic cerium-doped nano-hydroxyapatite/chitosan layered composite scaffolds regulate bone regeneration via OPG/RANKL signaling pathway

Abstract Autogenous bone grafting has long been considered the gold standard for treating critical bone defects. However, its use is plagued by numerous drawbacks, such as limited supply, donor site morbidity, and restricted use for giant-sized defects. For this reason, there is an increasing need f...

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Autores principales:	Xiao-Liang Liu, Chuan-Jian Zhang, Jing-Jing Shi, Qin-Fei Ke, Yu-Wei Ge, Zhen-An Zhu, Ya-Ping Guo
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2023-08-01
Colección:	Journal of Nanobiotechnology
Materias:	Layered Nacre-mimetic Bone regeneration Cerium Hydroxyapatite nanosheets
Acceso en línea:	https://doi.org/10.1186/s12951-023-01988-y
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