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CD4+ T cell expression of the IL-10 receptor is necessary for facial motoneuron survival after axotomy

Abstract Background After peripheral nerve transection, facial motoneuron (FMN) survival depends on an intact CD4+ T cell population and a central source of interleukin-10 (IL-10). However, it has not been determined previously whether CD4+ T cells participate in the central neuroprotective IL-10 ca...

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Autores principales: Elizabeth M. Runge, Abhirami K. Iyer, Deborah O. Setter, Felicia M. Kennedy, Virginia M. Sanders, Kathryn J. Jones
Formato: Artigo
Lenguaje:Inglês
Publicado: BMC 2020-04-01
Colección:Journal of Neuroinflammation
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Acceso en línea:http://link.springer.com/article/10.1186/s12974-020-01772-x
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