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Association between DNA Methylation of the BDNF Promoter Region and Clinical Presentation in Alzheimer's Disease

Background/Aims: In the present study, we examined whether DNA methylation of the brain-derived neurotrophic factor (BDNF) promoter is associated with the manifestation and clinical presentation of Alzheimer's disease (AD). Methods: Of 20 patients with AD and 20 age-matched normal controls (NCs), th...

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Kaydedildi:
Asıl Yazarlar: Tomoyuki Nagata, Nobuyuki Kobayashi, Jumpei Ishii, Shunichiro Shinagawa, Ritsuko Nakayama, Nobuto Shibata, Bolati Kuerban, Tohru Ohnuma, Kazuhiro Kondo, Heii Arai, Hisashi Yamada, Kazuhiko Nakayama
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Karger Publishers 2015-03-01
Seri Bilgileri:Dementia and Geriatric Cognitive Disorders Extra
Konular:
Epigenetics
Brain-derived neurotrophic factor
Alzheimerߣs disease
BDNF
DNA methylation
Neurotrophic factors
Online Erişim:http://www.karger.com/Article/FullText/375367
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