Copy number variation of IL17RA gene and its association with the ankylosing spondylitis risk in Iranian patients: a case-control study

Abstract Background Ankylosing spondylitis (AS) is considered as a subtype of spondyloarthritis (SpA) that mainly leads to fatigue, stiffness, spinal ankylosis, and impaired physical functions with reduced quality of life. Interleukin (IL)-17A provokes additional inflammatory mediators and recruits...

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Главные авторы:	Hamideh Aghaei, Elham Farhadi, Maryam Akhtari, Sara Shahba, Shayan Mostafaei, Ahmadreza Jamshidi, Shiva Poursani, Mahdi Mahmoudi, Mohammad Hossein Nicknam
Формат:	Artigo
Язык:	Inglês
Опубликовано:	BMC 2020-07-01
Серии:	BMC Medical Genetics
Предметы:	Ankylosing spondylitis Autoimmunity Copy number variations Gene expression IL17RA
Online-ссылка:	http://link.springer.com/article/10.1186/s12881-020-01078-y
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