Phosphatase PP2A enhances MCL-1 protein half-life in multiple myeloma cells
Abstract Multiple myeloma (MM), a treatable but incurable malignancy, is characterized by the growth of clonal plasma cells in protective niches in the bone marrow. MM cells depend on expression of BCL-2 family proteins, in particular MCL-1, for survival. The regulation of MCL-1 is complex and cell...
-д хадгалсан:
| Үндсэн зохиолчид: | , , , , , |
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| Формат: | Artigo |
| Хэл сонгох: | Inglês |
| Хэвлэсэн: |
Nature Publishing Group
2021-03-01
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| Цуврал: | Cell Death and Disease |
| Онлайн хандалт: | https://doi.org/10.1038/s41419-020-03351-7 |
| Шошгууд: |
Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!
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