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Molecular Dynamics Simulation Combined with Neural Relationship Inference and Markov Model to Reveal the Relationship between Conformational Regulation and Bioluminescence Properties of <i>Gaussia</i> Luciferase

<i>Gaussia</i> luciferase (Gluc) is currently known as the smallest naturally secreted luciferase. Due to its small molecular size, high sensitivity, short half-life, and high secretion efficiency, it has become an ideal reporter gene and is widely used in monitoring promoter activity, studying prot...

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Principais autores: Xiaotang Yang, Ruoyu Zhang, Weiwei Han, Lu Han
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2024-08-01
coleção:Molecules
Assuntos:
<i>Gaussia</i> luciferase (Gluc)
bioluminescence
molecular dynamics simulations
Markov model
conformational changes
neural relationship inference
Acesso em linha:https://www.mdpi.com/1420-3049/29/17/4029
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