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Direct Reprogramming of Cardiac Fibroblasts to Repair the Injured Heart

Coronary heart disease is a leading cause of mortality and morbidity. Those that survive acute myocardial infarction are at significant risk of subsequent heart failure due to fibrotic remodelling of the infarcted myocardium. By applying knowledge from the study of embryonic cardiovascular developme...

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Autori principali: Emma Adams, Rachel McCloy, Ashley Jordan, Kaitlin Falconer, Iain M. Dykes
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2021-06-01
Serie:Journal of Cardiovascular Development and Disease
Soggetti:
reprogramming
stem cell
regenerative medicine
induced pluripotent stem cell
myocardial infarction
heart failure
Accesso online:https://www.mdpi.com/2308-3425/8/7/72
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