In silico Analysis of SARS-CoV-2 ORF8-Binding Proteins Reveals the Involvement of ORF8 in Acquired-Immune and Innate-Immune Systems

SARS-CoV-2 is the causative agent of a new type of coronavirus infection, COVID-19, which has rapidly spread worldwide. The overall genome sequence homology between SARS-CoV-2 and SARS-CoV is 79%. However, the homology of the ORF8 protein between these two coronaviruses is low, at ~26%. Previously,...

Полное описание

Библиографические подробности

Главные авторы:	Hisashi Takatsuka, Muhamad Fahmi, Kotono Hamanishi, Takuya Sakuratani, Yukihiko Kubota, Masahiro Ito
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Frontiers Media S.A. 2022-02-01
Серии:	Frontiers in Medicine
Предметы:	SARS-CoV-2 phylogenetic profiling immune evasion COVID-19 pathogenesis ORF8 accessory gene
Online-ссылка:	https://www.frontiersin.org/articles/10.3389/fmed.2022.824622/full
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