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Zebrafish Avatars of rectal cancer patients validate the radiosensitive effect of metformin

Neoadjuvant chemoradiation (nCRT) followed by surgery represents the standard of care in patients with locally advanced rectal cancer. Increasing radiotherapy (RT) doses and chemotherapy cycles with 5FU have been associated with increased rates of complete response, however these strategies imply si...

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Autors principals: Bruna Costa, Laura M. Fernandez, Oriol Parés, Ricardo Rio-Tinto, Inês Santiago, Mireia Castillo-Martin, Amjad Parvaiz, Rita Fior
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2022-09-01
Col·lecció:Frontiers in Oncology
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Accés en línia:https://www.frontiersin.org/articles/10.3389/fonc.2022.862889/full
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