Mesenchymal stromal cells protect combined oncolytic and helper-dependent adenoviruses from humoral immunity

Systemic delivery of oncolytic and immunomodulatory adenoviruses may be required for optimal effects on human malignancies. Mesenchymal stromal cells (MSCs) can serve as delivery systems for cancer therapeutics due to their ability to transport and shield these agents while homing to tumors. We now...

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Autori principali:	Ada Irmak Özcan, Arianexys Aquino Lόpez, Alexandra N. Wolff, Audrey Ma, Amanda Rosewell Shaw, Masataka Suzuki, Malcolm K. Brenner, Mary K. McKenna
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2024-09-01
Serie:	Molecular Therapy: Methods & Clinical Development
Soggetti:	mesenchymal stromal cells oncolytic adenovirus helper-dependent adenovirus three-dimensional tumor spheroids solid tumors
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2329050124000950
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