IFDlong: a model-based isoform and fusion detector for accurate annotation and quantification of long-read RNA-seq data

Abstract Long-read transcriptome sequencing (long-RNA-seq) revolutionizes transcriptome research by enabling full-length transcript analysis for comprehensive exploration of isoform diversity. We developed IFDlong, a probabilistic framework and software suite for detecting isoform and fusion transcr...

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Bibliografische Detailangaben

Hauptverfasser:	Wenjia Wang, Jia-Jun Liu, Yuzhen Li, Sungjin Ko, Ning Feng, Manling Zhang, Qingqi Lin, Mengying Xia, Yan P. Yu, Jian-Hua Luo, Pedro L. Baldoni, George C. Tseng, Silvia Liu
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2026-03-01
Schriftenreihe:	Genome Biology
Schlagworte:	Long-read RNA-seq Isoform Alternative splicing Fusion transcript Single-cell sequencing
Online-Zugang:	https://doi.org/10.1186/s13059-026-04023-z
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