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Tertiary lymphoid structures in the microenvironment of colorectal cancer: exploring new therapeutic targets

Abstract Immunotherapy has shown limited efficacy in colorectal cancer (CRC), necessitating the urgent identification of novel immunotherapeutic targets to address this challenge. Tertiary lymphoid structures (TLSs) are complex immune structures that spontaneously form within and outside of the tumo...

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Bibliografiske detaljer
Principais autores: Nan-Nan Dai, Man-Yi Hu, Jian-Ping Wang, Zhi-Hui Dai, Li Xu, Tai-Wei Ye
Format: Artigo
Sprog:Inglês
Udgivet: Springer 2025-06-01
Serier:Cancer Immunology, Immunotherapy
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Online adgang:https://doi.org/10.1007/s00262-025-04108-x
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