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Dual Effects of miR-181b-2-3p/SOX21 Interaction on Microglia and Neural Stem Cells after Gamma Irradiation

Ionizing radiation induces brain inflammation and the impairment of neurogenesis by activating microglia and inducing apoptosis in neurogenic zones. However, the causal relationship between microglial activation and the impairment of neurogenesis as well as the relevant molecular mechanisms involved...

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Principais autores: Hong Wang, Zhao-Wu Ma, Feng-Ming Ho, Gautam Sethi, Feng Ru Tang
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2023-02-01
Serier:Cells
Fag:
γ-irradiation
microglia activation
neurogenesis
miR-181b-2-3p
SOX21
Online adgang:https://www.mdpi.com/2073-4409/12/4/649
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