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Hydrogen gas with hypothermic machine perfusion induces lipidomic alterations in donation-after-cardiac-death rat livers

Hypothermic machine perfusion (HMP) combined with hydrogen gas has previously been shown to mitigate ischemia-reperfusion injury (IRI) in rat liver, but without full recovery of function. This study examined how hydrogen gas modulates hepatic lipid metabolism during HMP using donation after cardiac...

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Principais autores: Yusuke Minami, Siddabasave Gowda B. B. Gowda, Kengo Shibata, Sodai Sakamoto, Divyavani Gowda, Tsuyoshi Shimamura, Akinobu Taketomi, Hitoshi Chiba, Moto Fukai, Shu-Ping Hui
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2026-06-01
coleção:Journal of Lipid Research
Assuntos:
ischemia reperfusion injury
lipid metabolism
lipidomics
lysophospholipid
mitochondria
phosphatidic acid
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S0022227526000660
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