Efficacy of third-line chemotherapy following nanoliposomal irinotecan combined with fluorouracil and folinic acid as second-line treatment for unresectable pancreatic cancer

IntroductionThe significance of third-line chemotherapy (CTx) in unresectable pancreatic cancer (UPC) remains unclear. This study evaluated the therapeutic impact of third-line CTx after nanoliposomal irinotecan and fluorouracil combined with folinic acid (nal-IRI + 5-FU/LV) therapy as second-line C...

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Hlavní autoři:	Keisuke Miwa, Reina Kawasaki, Mototsugu Shimokawa, Taiga Otsuka, Toshimitsu Tanaka, Masaru Fukahori, Taro Shibuki, Junichi Nakazawa, Shiho Arima, Futa Koga, Yujiro Ueda, Yoshihito Kubotsu, Hozumi Shimokawa, Shigeyuki Takeshita, Kazuo Nishikawa, Azusa Komori, Satoshi Otsu, Ayumu Hosokawa, Tatsunori Sakai, Hisanobu Oda, Machiko Kawahira, Shuji Arita, Takuya Honda, Hiroki Taguchi, Kengo Tsuneyoshi, Toshihiro Fujita, Takahiro Sakae, Yasunori Kawaguchi, Tsuyoshi Shirakawa, Toshihiko Mizuta, Kenji Mitsugi
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2025-07-01
Edice:	Frontiers in Oncology
Témata:	pancreatic cancer chemotherapy third-line treatment nanoliposomal irinotecan best supportive care
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fonc.2025.1626689/full
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