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Statistical reanalysis of vascular event outcomes in primary and secondary vascular prevention trials

Abstract Background Vascular prevention trials typically use dichotomous event outcomes although this may be inefficient statistically and gives no indication of event severity. We assessed whether ordinal outcomes would be more efficient and how to best analyse them. Methods Chief investigators of...

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Principais autores: Lisa J. Woodhouse, Alan A. Montgomery, Jonathan Mant, Barry R. Davis, Ale Algra, Jean-Louis Mas, Jan A. Staessen, Lutgarde Thijs, Andrew Tonkin, Adrienne Kirby, Stuart J. Pocock, John Chalmers, Graeme J. Hankey, J. David Spence, Peter Sandercock, Hans-Christoph Diener, Shinichiro Uchiyama, Nikola Sprigg, Philip M. Bath
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2021-10-01
Series:BMC Medical Research Methodology
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Acceso en liña:https://doi.org/10.1186/s12874-021-01388-6
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