Androgen Receptor-CaMKK2 Axis in Prostate Cancer and Bone Microenvironment

The skeletal system is of paramount importance in advanced stage prostate cancer (PCa) as it is the preferred site of metastasis. Complex mechanisms are employed sequentially by PCa cells to home to and colonize the bone. Bone-resident PCa cells then recruit osteoblasts (OBs), osteoclasts (OCs), and...

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Κύριοι συγγραφείς:	Ushashi C. Dadwal, Eric S. Chang, Uma Sankar
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Frontiers Media S.A. 2018-06-01
Σειρά:	Frontiers in Endocrinology
Θέματα:	castrate-resistant prostate cancer androgen-deprivation therapy CAMKK2 bone–tumor microenvironment treatment induced bone loss
Διαθέσιμο Online:	https://www.frontiersin.org/article/10.3389/fendo.2018.00335/full
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