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Helminth coinfections mitigate clinical, parasitological, and immune outcomes in Mozambican children with malaria

Abstract Background Clearance of Plasmodium falciparum infection requires a TH1 immune response with production of pro-inflammatory cytokines, IgG1, and IgG3 responses. In contrast, infections with helminths are dominated by TH2/Treg immune responses characterized by production of anti-inflammatory...

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Principais autores: Inocência Cuamba, Rebeca Santano, Berta Grau-Pujol, Marta Vidal, Ruth Aguilar, Anélsio Cossa, Chenjerai Jairoce, Rojelio Mejia, Augusto Nhabomba, Jose Muñoz, Gemma Moncunill, Carlota Dobaño
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2026-03-01
Serier:BMC Medicine
Fag:
Plasmodium falciparum
Helminth
Coinfection
Immunomodulation
Online adgang:https://doi.org/10.1186/s12916-026-04827-7
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