Deficiency of Nuclear Receptor Coactivator 3 Aggravates Diabetic Kidney Disease by Impairing Podocyte Autophagy

Abstract Nuclear receptors (NRs) are important transcriptional factors that mediate autophagy, preventing podocyte injury and the progression of diabetic kidney disease (DKD). However, the role of nuclear receptor coactivators that are powerful enhancers for the transcriptional activity of NRs in DK...

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Detalhes bibliográficos

Principais autores:	Yaru Xie, Qian Yuan, Xinyi Cao, Yang Qiu, Jieyu Zeng, Yiling Cao, Yajuan Xie, Xianfang Meng, Kun Huang, Fan Yi, Chun Zhang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2024-05-01
coleção:	Advanced Science
Assuntos:	autophagy diabetic kidney disease nuclear receptor coactivator peroxisome proliferator‐activated receptor ‐γ podocyte
Acesso em linha:	https://doi.org/10.1002/advs.202308378
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