Adenosine signaling mediates hypoxic responses in the chronic lymphocytic leukemia microenvironment

Abstract: The chronic lymphocytic leukemia (CLL) niche is a closed environment where leukemic cells derive growth and survival signals through their interaction with macrophages and T lymphocytes. Here, we show that the CLL lymph node niche is characterized by overexpression and activation of HIF-1α...

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Autors principals:	Sara Serra, Tiziana Vaisitti, Valentina Audrito, Cinzia Bologna, Roberta Buonincontri, Shih-Shih Chen, Francesca Arruga, Davide Brusa, Marta Coscia, Ozren Jaksic, Giorgio Inghirami, Davide Rossi, Richard R. Furman, Simon C. Robson, Gianluca Gaidano, Nicholas Chiorazzi, Silvia Deaglio
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2016-11-01
Col·lecció:	Blood Advances
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2473952920303694
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