In vitro and in silico assessment of the effect of WWOX expression on invasiveness pathways associated with AP-2 transcription factors in bladder cancer

Abstract Background WW Domain Containing Oxidoreductase (WWOX) belongs to the unusual tumor suppressors, whose molecular function is not fully understood in bladder cancer, especially regarding interaction with Activator Protein 2 (AP-2) α/γ transcription factors. Thus, using lentiviral systems we c...

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Hauptverfasser:	Żaneta Kałuzińska, Damian Kołat, Katarzyna Kośla, Magdalena Orzechowska, Andrzej K. Bednarek, Elżbieta Płuciennik
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2021-03-01
Schriftenreihe:	BMC Urology
Schlagworte:	Bladder cancer WWOX TFAP2A TFAP2C AP-2alpha AP-2gamma
Online-Zugang:	https://doi.org/10.1186/s12894-021-00806-7
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