Influence of ?S-globin haplotypes and hydroxyurea on tumor necrosis factor-alpha levels in sickle cell anemia
Background: Sickle cell anemia is a chronic inflammatory disease characterized by an increased production of proinflammatory cytokines including tumor necrosis factor-alpha. Hydroxyurea, by decreasing the polymerization of hemoglobin, reduces inflammatory states. The effect of the genetic polymorphi...
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Elsevier
2014-04-01
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| Series: | Revista Brasileira de Hematologia e Hemoterapia |
| Assuntos: | |
| Acceso en liña: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842014000200121&lng=en&tlng=en |
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