Spatial Organization of Chromatin: Transcriptional Control of Adaptive Immune Cell Development

Higher-order spatial organization of the genome into chromatin compartments (permissive and repressive), self-associating domains (TADs), and regulatory loops provides structural integrity and offers diverse gene regulatory controls. In particular, chromatin regulatory loops, which bring enhancer an...

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Автори:	Jagan M. R. Pongubala, Cornelis Murre
Формат:	Artigo
Мова:	Inglês
Опубліковано:	Frontiers Media S.A. 2021-03-01
Серія:	Frontiers in Immunology
Предмети:	chromatin organization cis-regulatory interactions gene regulatory networks phase-separation B and T cell development
Онлайн доступ:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.633825/full
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