Long-Timescale Dynamics and Regulation of Sec-Facilitated Protein Translocation
We present a coarse-grained modeling approach that spans the nanosecond- to minute-timescale dynamics of cotranslational protein translocation. The method enables direct simulation of both integral membrane protein topogenesis and transmembrane domain (TM) stop-transfer efficiency. Simulations revea...
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| Principais autores: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2012-10-01
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| coleção: | Cell Reports |
| Acesso em linha: | http://www.sciencedirect.com/science/article/pii/S221112471200280X |
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