MALAT1-dependent hsa_circ_0076611 regulates translation rate in triple-negative breast cancer
The circular isoform of VEGFA mRNA (circ_0076611), associated with size and pathogenesis of triple-negative breast tumors, is produced via back splicing of exon-7 by a RNP complex comprising lncRNA-MALAT1, ID4 and SRSF1, and secreted through exosomes.
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| Principais autores: | , , , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Portfolio
2022-06-01
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| coleção: | Communications Biology |
| Acesso em linha: | https://doi.org/10.1038/s42003-022-03539-x |
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