Structure of the human galanin receptor 2 bound to galanin and Gq reveals the basis of ligand specificity and how binding affects the G-protein interface.

Galanin is a neuropeptide expressed in the central and peripheral nervous systems, where it regulates various processes including neuroendocrine release, cognition, and nerve regeneration. Three G-protein coupled receptors (GPCRs) for galanin have been discovered, which is the focus of efforts to tr...

Cijeli opis

Bibliografski detalji

Glavni autori:	Yunseok Heo, Naito Ishimoto, Ye-Eun Jeon, Ji-Hye Yun, Mio Ohki, Yuki Anraku, Mina Sasaki, Shunsuke Kita, Hideo Fukuhara, Tatsuya Ikuta, Kouki Kawakami, Asuka Inoue, Katsumi Maenaka, Jeremy R H Tame, Weontae Lee, Sam-Yong Park
Format:	Artigo
Jezik:	Inglês
Izdano:	Public Library of Science (PLoS) 2022-08-01
Serija:	PLoS Biology
Online pristup:	https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3001714&type=printable
Oznake:	Dodaj oznaku Bez oznaka, Budi prvi tko označuje ovaj zapis!