Treatment with oclacitinib, a Janus kinase inhibitor, down-regulates and up-regulates CD25 and Foxp3 expression, respectively, in peripheral blood T cells of dogs with atopic dermatitis
Abstract Background Oclacitinib (OCL), a Janus kinase inhibitor, is a novel immunomodulatory/immunosuppressive agent which is an approved as the first-line treatment for atopic dermatitis (AD) in dogs. The aim of the study was to investigate the effects of OCL on CD4+ and CD8+ T cells and their sele...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
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BMC
2024-10-01
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| Schriftenreihe: | BMC Veterinary Research |
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| Online-Zugang: | https://doi.org/10.1186/s12917-024-04340-0 |
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