Design, synthesis, and antiproliferative activity of new 5-ethylsulfonyl-indazole-3-carbohydrazides as dual EGFR/VEGFR-2 kinases inhibitors
A novel series of 5-ethylsulfonyl-indazole-3-carbohydrazides 7a–o, serving as dual inhibitors of EGFR and VEGFR-2 was developed. The antiproliferative effects of compounds 7a–o were assessed against four cancer cell lines via the MTT assay. Compounds 7g, 7i–7l, and 7o emerged as the most efficient s...
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Taylor & Francis Group
2025-12-01
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| Series: | Journal of Enzyme Inhibition and Medicinal Chemistry |
| Assuntos: | |
| Acceso en liña: | https://www.tandfonline.com/doi/10.1080/14756366.2025.2516075 |
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