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A Gene Prognostic Index Associated With Epithelial-Mesenchymal Transition Predicting Biochemical Recurrence and Tumor Chemoresistance for Prostate Cancer

BackgroundWe aimed to establish a novel epithelial-mesenchymal transition (EMT)-related gene prognostic index (EMTGPI) associated with biochemical recurrence (BCR) and drug resistance for prostate cancer (PCa).MethodsWe used Lasso and Cox regression analysis to establish the EMTGPI. All analyses wer...

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Principais autores: Dechao Feng, Xu Shi, Qiao Xiong, Facai Zhang, Dengxiong Li, Lu Yang
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2022-01-01
Serier:Frontiers in Oncology
Fag:
epithelial-mesenchymal transition
prostate cancer
tumor immune microenvironment
biochemical recurrence
tumor chemoresistance
immune checkpoint
Online adgang:https://www.frontiersin.org/articles/10.3389/fonc.2021.805571/full
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