Levodopa Rescues Retinal Function in the Transgenic A53T Alpha-Synuclein Model of Parkinson’s Disease

Background: Loss of substantia nigra dopaminergic cells and alpha-synuclein (α-syn)-rich intraneuronal deposits within the central nervous system are key hallmarks of Parkinson’s disease (PD). Levodopa (L-DOPA) is the current gold-standard treatment for PD. This study aimed to evaluate <i>in vivo</i...

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Bibliographic Details

Main Authors:	Katie K. N. Tran, Vickie H. Y. Wong, Kirstan A. Vessey, David I. Finkelstein, Bang V. Bui, Christine T. O. Nguyen
Format:	Artigo
Language:	Inglês
Published:	MDPI AG 2024-01-01
Series:	Biomedicines
Subjects:	A53T mice levodopa Parkinson’s disease electroretinography optical coherence tomography amacrine cells
Online Access:	https://www.mdpi.com/2227-9059/12/1/130
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