scCASE: accurate and interpretable enhancement for single-cell chromatin accessibility sequencing data

Abstract Single-cell chromatin accessibility sequencing (scCAS) has emerged as a valuable tool for interrogating and elucidating epigenomic heterogeneity and gene regulation. However, scCAS data inherently suffers from limitations such as high sparsity and dimensionality, which pose significant chal...

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Hlavní autoři:	Songming Tang, Xuejian Cui, Rongxiang Wang, Sijie Li, Siyu Li, Xin Huang, Shengquan Chen
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2024-02-01
Edice:	Nature Communications
On-line přístup:	https://doi.org/10.1038/s41467-024-46045-w
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