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Identification of function-regulating antibodies targeting the receptor protein tyrosine phosphatase sigma ectodomain.

Receptor tyrosine phosphatase sigma (RPTPσ) plays an important role in the regulation of axonal outgrowth and neural regeneration. Recent studies have identified two RPTPσ ligands, chondroitin sulfate proteoglycans (CSPGs) and heparan sulfate proteoglycans (HSPG), which can modulate RPTPσ activity b...

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Váldodahkkit: Chia-Lun Wu, Serge Hardy, Isabelle Aubry, Melissa Landry, Allison Haggarty, Horacio Uri Saragovi, Michel L Tremblay
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Public Library of Science (PLoS) 2017-01-01
Ráidu:PLoS ONE
Liŋkkat:http://europepmc.org/articles/PMC5449173?pdf=render
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