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Crosstalk between autophagy inhibitors and endosome-related secretory pathways: a challenge for autophagy-based treatment of solid cancers

Abstract Autophagy is best known for its role in organelle and protein turnover, cell quality control, and metabolism. The autophagic machinery has, however, also adapted to enable protein trafficking and unconventional secretory pathways so that organelles (such as autophagosomes and multivesicular...

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Autori principali: Martina Raudenska, Jan Balvan, Michal Masarik
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2021-10-01
Serie:Molecular Cancer
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Accesso online:https://doi.org/10.1186/s12943-021-01423-6
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