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A Mouse Model of Mild <i>Clostridioides difficile</i> Infection for the Characterization of Natural Immune Responses

(1) Background: We describe a model of primary mild-<i>Clostridioides difficile</i> infection (CDI) in a naïve host, including gut microbiota analysis, weight loss, mortality, length of colonization. This model was used in order to describe the kinetics of humoral (IgG, IgM) and mucosal (IgA) immune...

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Main Authors: Assaf Mizrahi, Gauthier Péan de Ponfilly, Diane Sapa, Antonia Suau, Irène Mangin, Aurélie Baliarda, Sandra Hoys, Benoît Pilmis, Sylvie Lambert, Anaïs Brosse, Alban Le Monnier
Format: Artigo
Language:Inglês
Published: MDPI AG 2024-09-01
Series:Microorganisms
Subjects:
<i>Clostridioides difficile</i>
immune response
colonization factor
toxins
gut microbiota
Online Access:https://www.mdpi.com/2076-2607/12/10/1933
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