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Tumor immune microenvironment and immunotherapy efficacy in BRAF mutation non-small-cell lung cancer

Abstract Previous small-size studies reported BRAF-mutated NSCLC patients have comparable sensitivity to immune checkpoint inhibitors (ICIs). However, how BRAF mutation affects the tumor immune microenvironment (TIME) is unknown. We performed Nanostring-panel RNA sequencing to evaluate TIME in 57 BR...

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Autori principali: Hui Li, Yongchang Zhang, Yanjun Xu, Zhiyu Huang, Guoping Cheng, Mingyin Xie, Zichao Zhou, Yangyang Yu, Wenjing Xi, Yun Fan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2022-12-01
Serie:Cell Death and Disease
Accesso online:https://doi.org/10.1038/s41419-022-05510-4
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