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PARP Inhibitors for the Treatment of BRCA1/ 2-Mutated Metastatic Breast Cancer: A Systematic Review and Meta-analysis

Background: The PARP inhibitors (PARPis) olaparib and talazoparib are currently approved for the treatment of deleterious germline BRCA1/2-mutated (gBRCA+) metastatic breast cancer (MBC). These approvals were based on improvements in progression-free survival (PFS) observed in two randomized control...

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Autores principales: Ranju Kunwor, Daniel P. Silver, Maysa Abu-Khalaf
Formato: Artigo
Lenguaje:Inglês
Publicado: Wolters Kluwer Medknow Publications 2023-07-01
Colección:Hematology/Oncology and Stem Cell Therapy
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Acceso en línea:https://journals.lww.com/10.56875/2589-0646.1033
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