Cellular Growth Arrest and Efflux Pumps Are Associated With Antibiotic Persisters in Streptococcus pyogenes Induced in Biofilm-Like Environments

Streptococcus pyogenes (group A Streptococcus-GAS) is an important pathogen for humans. GAS has been associated with severe and invasive diseases. Despite the fact that these bacteria remain universally susceptible to penicillin, therapeutic failures have been reported in some GAS infections. Many h...

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Hlavní autoři:	Caroline Lopes Martini, Amada Zambrana Coronado, Maria Celeste Nunes Melo, Clarice Neffa Gobbi, Úrsula Santos Lopez, Marcos Correa de Mattos, Thais Tavares Amorim, Ana Maria Nunes Botelho, Ana Tereza Ribeiro Vasconcelos, Luiz Gonzaga Paula Almeida, Paul J. Planet, Russolina Benedeta Zingali, Agnes Marie Sá Figueiredo, Bernadete Teixeira Ferreira-Carvalho
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2021-09-01
Edice:	Frontiers in Microbiology
Témata:	Streptococcus pyogenes drug refractory persisters efflux pump antimicrobial resistance clinical resistance
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fmicb.2021.716628/full
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