Interleukin-36 cytokines alter the intestinal microbiome and can protect against obesity and metabolic dysfunction

IL-36α,β and ɣ are IL-1-related cytokines promoting inflammation in the skin and intestine. Here the authors show they are elevated in individuals with obesity, and that mice lacking the IL-36 receptor antagonist are more resistant to diet-induced obesity and metabolic dysfunction, which depends on...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Eirini Giannoudaki, Yasmina E. Hernandez-Santana, Kelly Mulfaul, Sarah L. Doyle, Emily Hams, Padraic G. Fallon, Arimin Mat, Donal O’Shea, Manfred Kopf, Andrew E. Hogan, Patrick T. Walsh
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Nature Portfolio 2019-09-01
Σειρά:	Nature Communications
Διαθέσιμο Online:	https://doi.org/10.1038/s41467-019-11944-w
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