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Colorectal Cancer Cell Invasion and Functional Properties Depend on Peri-Tumoral Extracellular Matrix

We investigated how the extracellular matrix (ECM) affects LoVo colorectal cancer cells behavior during a spatiotemporal invasion. Epithelial-to-mesenchymal transition (EMT) markers, matrix-degrading enzymes, and morphological phenotypes expressed by LoVo-S (doxorubicin-sensitive) and higher aggress...

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Bibliographic Details
Main Authors: Marco Franchi, Konstantinos-Athanasios Karamanos, Concettina Cappadone, Natalia Calonghi, Nicola Greco, Leonardo Franchi, Maurizio Onisto, Valentina Masola
Format: Artigo
Language:Inglês
Published: MDPI AG 2023-06-01
Series:Biomedicines
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Online Access:https://www.mdpi.com/2227-9059/11/7/1788
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