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Proximity labelling of pro-interleukin-1α reveals evolutionary conserved nuclear interactions

Abstract Interleukin-1α is a suggested dual-function cytokine that diverged from interleukin-1β in mammals potentially by acquiring additional biological roles that relate to highly conserved regions in the pro-domain of interleukin-1α, including a nuclear localisation sequence and histone acetyltra...

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Bibliografski detalji
Glavni autori: Rose Wellens, Victor S. Tapia, Paula I. Seoane, Hayley Bennett, Antony Adamson, Graham Coutts, Jack Rivers-Auty, Martin Lowe, Jack P. Green, Gloria Lopez-Castejon, David Brough, Christopher Hoyle
Format: Artigo
Jezik:Inglês
Izdano: Nature Portfolio 2024-08-01
Serija:Nature Communications
Online pristup:https://doi.org/10.1038/s41467-024-50901-0
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