Resistance and resilience to Alzheimer’s disease pathology are associated with reduced cortical pTau and absence of limbic-predominant age-related TDP-43 encephalopathy in a community-based cohort

Abstract Alzheimer’s disease neuropathologic change (ADNC) is defined by progressive accumulation of β-amyloid plaques and hyperphosphorylated tau (pTau) neurofibrillary tangles across diverse regions of brain. Non-demented individuals who reach advanced age without significant ADNC are considered t...

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主要な著者:	Caitlin S. Latimer, Bridget T. Burke, Nicole F. Liachko, Heather N. Currey, Mitchell D. Kilgore, Laura E. Gibbons, Jonathan Henriksen, Martin Darvas, Kimiko Domoto-Reilly, Suman Jayadev, Tom J. Grabowski, Paul K. Crane, Eric B. Larson, Brian C. Kraemer, Thomas D. Bird, C. Dirk Keene
フォーマット:	Artigo
言語:	Inglês
出版事項:	BMC 2019-06-01
シリーズ:	Acta Neuropathologica Communications
主題:	Resistance Resilience Alzheimer’s disease neuropathologic change TDP-43 Hyperphosphorylated tau Dementia
オンライン･アクセス:	http://link.springer.com/article/10.1186/s40478-019-0743-1
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