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Novel triazine JPC-2067-B inhibits Toxoplasma gondii in vitro and in vivo.

Toxoplasma gondii causes substantial morbidity, mortality, and costs for healthcare in the developed and developing world. Current medicines are not well tolerated and cause hypersensitivity reactions. The dihydrotriazine JPC-2067-B (4, 6-diamino-1, 2-dihydro-2, 2-dimethyl-1-(3'(2-chloro-, 4-trifluo...

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Principais autores: Ernest J Mui, Guy A Schiehser, Wilbur K Milhous, Honghue Hsu, Craig W Roberts, Michael Kirisits, Stephen Muench, David Rice, J P Dubey, Joseph W Fowble, Pradipsinh K Rathod, Sherry F Queener, Susan R Liu, David P Jacobus, Rima McLeod
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2008-03-01
coleção:PLoS Neglected Tropical Diseases
Acesso em linha:http://europepmc.org/articles/PMC2254147?pdf=render
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