A Toolbox for the Generation of Chemical Probes for Baculovirus IAP Repeat Containing Proteins

E3 ligases constitute a large and diverse family of proteins that play a central role in regulating protein homeostasis by recruiting substrate proteins via recruitment domains to the proteasomal degradation machinery. Small molecules can either inhibit, modulate or hijack E3 function. The latter cl...

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ग्रंथसूची विवरण

मुख्य लेखकों:	Martin P. Schwalm, Lena M. Berger, Maximilian N. Meuter, James D. Vasta, Cesear R. Corona, Sandra Röhm, Benedict-Tilman Berger, Frederic Farges, Sebastian M. Beinert, Franziska Preuss, Viktoria Morasch, Vladimir V. Rogov, Sebastian Mathea, Krishna Saxena, Matthew B. Robers, Susanne Müller, Stefan Knapp
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	Frontiers Media S.A. 2022-05-01
श्रृंखला:	Frontiers in Cell and Developmental Biology
विषय:	IAP E3 Ligase PROTAC Ubiquitin NanoBRET
ऑनलाइन पहुंच:	https://www.frontiersin.org/articles/10.3389/fcell.2022.886537/full
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