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From undruggable to actionable: advances in KRAS targeting in colorectal cancer

KRAS (Kristen rat sarcoma viral oncogene homolog) mutations occur in approximately 40–50% of metastatic colorectal cancer (CRC) cases and have long been associated with resistance to anti-epidermal growth factor receptor (EGFR) therapies and poor clinical outcomes. Historically considered...

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-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Mei Chan, Meghna Shelke, Amanda Townsend, Amitesh Roy, Vy Broadbridge, Christos Karapetis, Timothy Price
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: Academia.edu Journals 2026-04-01
Цуврал:Academia Oncology
Онлайн хандалт:https://www.academia.edu/165525801/From_undruggable_to_actionable_advances_in_KRAS_targeting_in_colorectal_cancer
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