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Comprehensive molecular characterization of TFE3-rearranged renal cell carcinoma

Abstract TFE3-rearranged renal cell cancer (tRCC) is a rare form of RCC that involves chromosomal translocation of the Xp11.2 TFE3 gene. Despite its early onset and poor prognosis, the molecular mechanisms of the pathogenesis of tRCC remain elusive. This study aimed to identify novel therapeutic tar...

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Principais autores: Cho-Rong Lee, Jungyo Suh, Dongjun Jang, Bo-Yeong Jin, Jaeso Cho, Moses Lee, Hyungtai Sim, Minyong Kang, Jueun Lee, Ju Hyun Park, Kyoung-Hwa Lee, Geum-Sook Hwang, Kyung Chul Moon, Cheryn Song, Ja Hyeon Ku, Cheol Kwak, Hyeon Hoe Kim, Sung-Yup Cho, Murim Choi, Chang Wook Jeong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2024-08-01
Colecção:Experimental and Molecular Medicine
Acesso em linha:https://doi.org/10.1038/s12276-024-01291-2
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