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Changes in Heme Levels During Acute Vaso-occlusive Crisis in Sickle Cell Anemia

Objective/Background: Sickle cell anemia (SCA) is associated with increased levels of extracellular heme, which is a key mediator of inflammation in this condition. Despite abundant evidence supporting this concept in cell and animal models, few studies addressed the association between heme levels...

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Автори: Evilazio Cunha Cardoso, Pedro Vieira Silva-Neto, Bidossessi Wilfried Hounkpe, Francine Chenou, Cintia Cristina Mateus Xerez Albuquerque, Nadja Pinto Garcia, Alexander Leonardo Silva-Junior, Adriana Malheiro, Purim Cesar, Franciele de Lima, Erich V. De Paula, Nelson Abrahim Fraiji
Формат: Artigo
Мова:Inglês
Опубліковано: Wolters Kluwer Medknow Publications 2023-04-01
Серія:Hematology/Oncology and Stem Cell Therapy
Предмети:
d-dimer
heme
sickle cell anemia
thromboembolism
vaso-occlusion
Онлайн доступ:https://journals.lww.com/10.1016/j.hemonc.2021.08.002
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