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Selenium Nephroprotection through Inhibition of PERKEIF2α- CHOP Pathway in Lead Intoxicated Male Rats

Background: Lead contamination has turned into a major concern as it serves no useful purpose in the human body. Its presence in the body can lead to toxic effects on different organs. Aim: The purpose of the present study is to examine the efficacy of selenium in mitigating leadinduced oxidative st...

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Main Authors: Wesam EL Bakly, Mohammed Hussin, Mangoud El Wakel, Marwa Rashed
Format: Artigo
Language:Inglês
Published: Ain Shams University, Faculty of Medicine, Forensic Medicine ; Clinical Toxicology Department 2021-07-01
Series:Ain Shams Journal of Forensic Medicine and Clinical Toxicology
Subjects:
Lead nephrotoxicity
selenium
nephroprotection
PERK
eIF2α
CHOP pathway
caspase
Online Access:https://ajfm.journals.ekb.eg/article_182694_dded84337ec32752a26b5723c4c3a36a.pdf
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