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Autoantibodies as predictors for immune-related adverse events in checkpoint inhibition therapy of metastatic melanoma

Background Immune checkpoint inhibitors have transformed melanoma therapy but frequently cause immune-related adverse events (irAEs), including colitis, that limit treatment. Reliable biomarkers predicting toxicity remain lacking.Methods In this retrospective, multicenter study, we analyzed pretreat...

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Bibliografiske detaljer
Principais autores: Jessica C Hassel, Benjamin Weide, Reinhard Dummer, Friedegund Meier, Claudia Pfoehler, Kilian Wistuba-Hamprecht, Johanna Mangana, Robin Reschke, Hans-Dieter Zucht, Peter Schulz-Knappe, Petra Budde, Lara-Elena Hakim-Meibodi, Carsten Schulz, Jasmin Richter, Manual Bräutigam, Claudia Gutjahr
Format: Artigo
Sprog:Inglês
Udgivet: BMJ Publishing Group 2026-01-01
Serier:Journal for ImmunoTherapy of Cancer
Online adgang:https://jitc.bmj.com/content/14/1/e013814.full
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